The C-Type Lectin of the Aggrecan G3 Domain Activates Complement

Excessive complement activation contributes to joint diseases such as rheumatoid arthritis and osteoarthritis during which cartilage proteins are fragmented and released into the synovial fluid. Some of these proteins and fragments activate complement, which may sustain inflammation. The G3 domain o...

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Bibliographic Details
Main Authors: Melin Fürst, Camilla, Mörgelin, Matthias, Vadstrup, Kasper, Heinegård, Dick, Aspberg, Anders, Blom, Anna M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626604/
https://ncbi.nlm.nih.gov/pubmed/23596522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061407
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