A Missense Mutation in the Aggrecan C-type Lectin Domain Disrupts Extracellular Matrix Interactions and Causes Dominant Familial Osteochondritis Dissecans

Osteochondritis dissecans is a disorder in which fragments of articular cartilage and subchondral bone dislodge from the joint surface. We analyzed a five-generation family in which affected members had autosomal-dominant familial osteochondritis dissecans. A genome-wide linkage analysis identified...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Stattin, Eva-Lena, Wiklund, Fredrik, Lindblom, Karin, Önnerfjord, Patrik, Jonsson, Björn-Anders, Tegner, Yelverton, Sasaki, Takako, Struglics, André, Lohmander, Stefan, Dahl, Niklas, Heinegård, Dick, Aspberg, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820178/
https://ncbi.nlm.nih.gov/pubmed/20137779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2009.12.018
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados