NC4 Domain of Cartilage-specific Collagen IX Inhibits Complement Directly Due to Attenuation of Membrane Attack Formation and Indirectly through Binding and Enhancing Activity of Complement Inhibitors C4B-binding Protein and Factor H

Collagen IX containing the N-terminal noncollagenous domain 4 (NC4) is unique to cartilage and a member of the family of fibril-associated collagens with both collagenous and noncollagenous domains. Collagen IX is located at the surface of fibrils formed by collagen II and a minor proportion of coll...

Full description

Saved in:
Bibliographic Details
Main Authors: Kalchishkova, Nikolina, Fürst, Camilla Melin, Heinegård, Dick, Blom, Anna M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151037/
https://ncbi.nlm.nih.gov/pubmed/21659506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.242834
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items