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Mapping in vivo topoisomerase I sites on simian virus 40 DNA: asymmetric distribution of sites on replicating molecules.
Complexes between simian virus 40 DNA and topoisomerase I (topo I) were isolated from infected cells treated with camptothecin. The topo I break sites were precisely mapped by primer extension from defined oligonucleotides. Of the 56 sites, 40 conform to the in vitro consensus sequence previously de...
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| 發表在: | Mol Cell Biol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
1989
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362630/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2540421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.2.541 |
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