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Spacing is crucial for coordination of domain functions within the simian virus 40 core origin of replication.

The simian virus 40 core origin of replication is composed of distinct domains that are bracketed by DNA spacers. We created a matched set of insertion mutations in spacer sites to study the spatial relationships among origin domains. Insertions larger than a single base pair severely inhibit replic...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Parsons, R, Tegtmeyer, P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288981/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1312612/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.1933-1942.1992
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