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Replication in the amplified dihydrofolate reductase domain in CHO cells may initiate at two distinct sites, one of which is a repetitive sequence element.

To study initiation of DNA replication in mammalian chromosomes, we have established a methotrexate-resistant Chinese hamster ovary cell line (CHOC 400) that contains approximately 1,000 copies of the early replicating dihydrofolate reductase (DHFR) domain. We have previously shown that DNA replicat...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Anachkova, B, Hamlin, J L
פורמט: Artigo
שפה:Inglês
יצא לאור: 1989
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC362629/
https://ncbi.nlm.nih.gov/pubmed/2710116
תגים: הוספת תג
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