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A Possible Interaction Between Systemic and Renal Angiotensinogen in the Control of Blood Pressure

BACKGROUND: Angiotensinogen (AGT) is synthesized in the liver and proximal tubule. AGT overexpression at either site might increase blood pressure (BP). We used transgenic mice with AGT overexpression in proximal tubule (K), liver (L), or both sites (KL) to determine the relative contributions of he...

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Detalhes bibliográficos
Main Authors: Ramkumar, Nirupama, Stuart, Deborah, Ying, Jian, Kohan, Donald E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626041/
https://ncbi.nlm.nih.gov/pubmed/23467203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hps078
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