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Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells.

Children with associated Wilms' tumor, aniridia, genitourinary malformations, and mental retardation (WAGR syndrome) frequently have a cytogenetically visible germ line deletion of chromosomal band 11p13. In accordance with the Knudson hypothesis of two-hit carcinogenesis, the absence of this chromo...

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Publicat a:Mol Cell Biol
Autors principals: Reeve, A E, Sih, S A, Raizis, A M, Feinberg, A P
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362601/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542777/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1799-1803.1989
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