Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells.

Children with associated Wilms' tumor, aniridia, genitourinary malformations, and mental retardation (WAGR syndrome) frequently have a cytogenetically visible germ line deletion of chromosomal band 11p13. In accordance with the Knudson hypothesis of two-hit carcinogenesis, the absence of this chromo...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Reeve, A E, Sih, S A, Raizis, A M, Feinberg, A P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362601/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1799-1803.1989
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