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Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells.
Children with associated Wilms' tumor, aniridia, genitourinary malformations, and mental retardation (WAGR syndrome) frequently have a cytogenetically visible germ line deletion of chromosomal band 11p13. In accordance with the Knudson hypothesis of two-hit carcinogenesis, the absence of this c...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362601/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542777/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1799 |
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