Type II diabetes increases mitochondrial DNA mutations in the left ventricle of the Goto-Kakizaki diabetic rat

Mitochondrial dysfunction has a significant role in the development of diabetic cardiomyopathy. Mitochondrial oxidant stress has been accepted as the singular cause of mitochondrial DNA (mtDNA) damage as an underlying cause of mitochondrial dysfunction. However, separate from a direct effect on mtDN...

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Main Authors: Hicks, S., Labinskyy, N., Piteo, B., Laurent, D., Mathew, J. E., Gupte, S. A., Edwards, J. G.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
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Call for Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625896/
https://ncbi.nlm.nih.gov/pubmed/23376826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00567.2012
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