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Role of NAD(P)H Oxidase in Superoxide Generation and Endothelial Dysfunction in Goto-Kakizaki (GK) Rats as a Model of Nonobese NIDDM

BACKGROUND: Cardiovascular disease is the leading cause of mortality in diabetics, and it has a complex etiology that operates on several levels. Endothelial dysfunction and increased generation of reactive oxygen species are believed to be an underlying cause of vascular dysfunction and coronary ar...

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Библиографические подробности
Главные авторы: Gupte, Sachin, Labinskyy, Nazar, Gupte, Rakhee, Csiszar, Anna, Ungvari, Zoltan, Edwards, John G.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909910/
https://ncbi.nlm.nih.gov/pubmed/20668682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011800
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