Inhibition of p38 MAPK attenuates renal atrophy and fibrosis in a murine renal artery stenosis model

Renal artery stenosis (RAS) is an important cause of chronic renal dysfunction. Recent studies have underscored a critical role for CCL2 (MCP-1)-mediated inflammation in the progression of chronic renal damage in RAS and other chronic renal diseases. In vitro studies have implicated p38 MAPK as a cr...

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Main Authors: Wang, Diping, Warner, Gina M., Yin, Ping, Knudsen, Bruce E., Cheng, Jingfei, Butters, Kim A., Lien, Karen R., Gray, Catherine E., Garovic, Vesna D., Lerman, Lilach O., Textor, Stephen C., Nath, Karl A., Simari, Robert D., Grande, Joseph P.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2013
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625852/
https://ncbi.nlm.nih.gov/pubmed/23364805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00706.2012
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