Inhibition of p38 MAPK attenuates renal atrophy and fibrosis in a murine renal artery stenosis model

Renal artery stenosis (RAS) is an important cause of chronic renal dysfunction. Recent studies have underscored a critical role for CCL2 (MCP-1)-mediated inflammation in the progression of chronic renal damage in RAS and other chronic renal diseases. In vitro studies have implicated p38 MAPK as a cr...

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Hlavní autoři: Wang, Diping, Warner, Gina M., Yin, Ping, Knudsen, Bruce E., Cheng, Jingfei, Butters, Kim A., Lien, Karen R., Gray, Catherine E., Garovic, Vesna D., Lerman, Lilach O., Textor, Stephen C., Nath, Karl A., Simari, Robert D., Grande, Joseph P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625852/
https://ncbi.nlm.nih.gov/pubmed/23364805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00706.2012
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