Loading...

Inhibition of p38 MAPK attenuates renal atrophy and fibrosis in a murine renal artery stenosis model

Renal artery stenosis (RAS) is an important cause of chronic renal dysfunction. Recent studies have underscored a critical role for CCL2 (MCP-1)-mediated inflammation in the progression of chronic renal damage in RAS and other chronic renal diseases. In vitro studies have implicated p38 MAPK as a cr...

Full description

Saved in:
Bibliographic Details
Main Authors: Wang, Diping, Warner, Gina M., Yin, Ping, Knudsen, Bruce E., Cheng, Jingfei, Butters, Kim A., Lien, Karen R., Gray, Catherine E., Garovic, Vesna D., Lerman, Lilach O., Textor, Stephen C., Nath, Karl A., Simari, Robert D., Grande, Joseph P.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625852/
https://ncbi.nlm.nih.gov/pubmed/23364805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00706.2012
Tags: Add Tag
No Tags, Be the first to tag this record!