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Gene targeting with retroviral vectors: recombination by gene conversion into regions of nonhomology.

We have designed and constructed integration-defective retroviral vectors to explore their potential for gene targeting in mammalian cells. Two nonoverlapping deletion mutants of the bacterial neomycin resistance (neo) gene were used to detect homologous recombination events between viral and chromo...

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Podrobná bibliografie
Vydáno v:Mol Cell Biol
Hlavní autoři: Ellis, J, Bernstein, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 1989
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362579/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2725520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1621-1627.1989
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