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Gene targeting with retroviral vectors: recombination by gene conversion into regions of nonhomology.

We have designed and constructed integration-defective retroviral vectors to explore their potential for gene targeting in mammalian cells. Two nonoverlapping deletion mutants of the bacterial neomycin resistance (neo) gene were used to detect homologous recombination events between viral and chromo...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Ellis, J, Bernstein, A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362579/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2725520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1621-1627.1989
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