Role of poly(A) polymerase in the cleavage and polyadenylation of mRNA precursor.

To determine the role of poly(A) polymerase in 3'-end processing of mRNA, the effect of purified poly(A) polymerase antibodies on endonucleolytic cleavage and polyadenylation was studied in HeLa nuclear extracts, using adenovirus L3 pre-mRNA as the substrate. Both Mg2+- and Mn2+-dependent reactions...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Terns, M P, Jacob, S T
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2566910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1435-1444.1989
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