Role of poly(A) polymerase in the cleavage and polyadenylation of mRNA precursor.
To determine the role of poly(A) polymerase in 3'-end processing of mRNA, the effect of purified poly(A) polymerase antibodies on endonucleolytic cleavage and polyadenylation was studied in HeLa nuclear extracts, using adenovirus L3 pre-mRNA as the substrate. Both Mg2+- and Mn2+-dependent reactions...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
1989
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2566910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1435-1444.1989 |
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