A majority of mice show long-term expression of a human beta-globin gene after retrovirus transfer into hematopoietic stem cells.
Murine bone marrow was infected with a high-titer retrovirus vector containing the human beta-globin and neomycin phosphotransferase genes. Anemic W/Wv mice were transplanted with infected marrow which in some cases had been exposed to the selective agent G418. Human beta-globin expression was monit...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362559/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2657395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1426-1434.1989 |
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