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A majority of mice show long-term expression of a human beta-globin gene after retrovirus transfer into hematopoietic stem cells.

Murine bone marrow was infected with a high-titer retrovirus vector containing the human beta-globin and neomycin phosphotransferase genes. Anemic W/Wv mice were transplanted with infected marrow which in some cases had been exposed to the selective agent G418. Human beta-globin expression was monit...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Bender, M A, Gelinas, R E, Miller, A D
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362559/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2657395/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.4.1426-1434.1989
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