Llwytho...

The Role of Protonation States in Ligand-Receptor Recognition and Binding

In this review we discuss the role of protonation states in receptor-ligand interactions, providing experimental evidences and computational predictions that complex formation may involve titratable groups with unusual pKa’s and that protonation states frequently change from unbound to bound states....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Petukh, Marharyta, Stefl, Shannon, Alexov, Emil
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625499/
https://ncbi.nlm.nih.gov/pubmed/23170880
Tagiau: Ychwanegu Tag
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