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Protonation and pK changes in protein-ligand binding
Formation of protein-ligand complexes causes various changes in both the receptor and the ligand. This review focuses on changes in pK and protonation states of ionizable groups that accompany protein-ligand binding. Physical origins of these effects are outlined, followed by a brief overview of the...
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| Gepubliceerd in: | Q Rev Biophys |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4437766/ https://ncbi.nlm.nih.gov/pubmed/23889892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033583513000024 |
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