Cargando...

Statistics and Physical Origins of pK and Ionization State Changes upon Protein-Ligand Binding

This work investigates statistical prevalence and overall physical origins of changes in charge states of receptor proteins upon ligand binding. These changes are explored as a function of the ligand type (small molecule, protein, and nucleic acid), and distance from the binding region. Standard con...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Aguilar, Boris, Anandakrishnan, Ramu, Ruscio, Jory Z., Onufriev, Alexey V.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830434/
https://ncbi.nlm.nih.gov/pubmed/20197041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.11.016
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!