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A Computational Study of Nucleosomal DNA Flexibility

Molecular dynamics simulations of the nucleosome core particle and its isolated DNA free in solution are reported. The simulations are based on the implicit solvent methodology and provide insights into the nature of large-scale structural fluctuations and flexibility of the nucleosomal DNA. In addi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ruscio, Jory Z., Onufriev, Alexey
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635688/
https://ncbi.nlm.nih.gov/pubmed/16891359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.082099
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