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A Computational Study of Nucleosomal DNA Flexibility

Molecular dynamics simulations of the nucleosome core particle and its isolated DNA free in solution are reported. The simulations are based on the implicit solvent methodology and provide insights into the nature of large-scale structural fluctuations and flexibility of the nucleosomal DNA. In addi...

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Detalhes bibliográficos
Main Authors: Ruscio, Jory Z., Onufriev, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635688/
https://ncbi.nlm.nih.gov/pubmed/16891359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.082099
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