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Protein Binding of Lopinavir and Ritonavir During Four Phases of Pregnancy: Implications for Treatment Guidelines
OBJECTIVE: To investigate the intraindividual pharmacokinetics of total (protein bound + unbound) and unbound lopinavir/ritonavir (LPV/RTV) and to assess whether the pediatric formulation (100mg/25mg) can overcome any pregnancy-associated changes. DESIGN: Prospective longitudinal pharmacokinetic (PK...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625477/ https://ncbi.nlm.nih.gov/pubmed/23221983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31827fd47e |
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