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Toward an atomistic description of the urea-denatured state of proteins
We present here the characterization of the structural, dynamics, and energetics of properties of the urea-denatured state of ubiquitin, a small prototypical soluble protein. By combining state-of-the-art molecular dynamics simulations with NMR and small-angle X-ray scattering data, we were able to:...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625277/ https://ncbi.nlm.nih.gov/pubmed/23536295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216589110 |
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