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Apoptosis inhibition by Bcl-2 gives way to autophagy in glucocorticoid-treated lymphocytes

Glucocorticosteroid hormones, including prednisone and dexamethasone (Dex), have been used to treat lymphoid malignancies for many years because they readily induce apoptosis in immature lymphocytes lacking Bcl-2. However, elevated expression of the anti-apoptotic protein Bcl-2 inhibits apoptosis an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Swerdlow, Sarah, McColl, Karen, Rong, Yiping, Lam, Minh, Gupta, Anu, Distelhorst, Clark W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625121/
https://ncbi.nlm.nih.gov/pubmed/18362516
Tagiau: Ychwanegu Tag
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