Features of Brain MRI in Dogs with Treated and Untreated Mucopolysaccharidosis Type I

The mucopolysaccharidosis type I (MPS I) dog model has been important in the development of therapies for human patients. We treated dogs with enzyme replacement therapy (ERT) by various approaches. Dogs assessed included untreated MPS I dogs, heterozygous carrier dogs, and MPS I dogs treated with i...

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Bibliographic Details
Main Authors: Vite, Charles H, Nestrasil, Igor, Mlikotic, Anton, Jens, Jackie K, Snella, Elizabeth M, Gross, William, Shapiro, Elsa G, Kovac, Victor, Provenzale, James M, Chen, Steven, Le, Steven Q, Kan, Shih-hsin, Banakar, Shida, Wang, Raymond Y, Haskins, Mark E, Ellinwood, N Matthew, Dickson, Patricia I
Format: Artigo
Language:Inglês
Published: American Association for Laboratory Animal Science 2013
Subjects:
Canine Models
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625057/
https://ncbi.nlm.nih.gov/pubmed/23582423
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