Diffusion tensor imaging and myelin composition analysis reveal abnormal myelination in corpus callosum of canine mucopolysaccharidosis I

Children with mucopolysaccharidosis I (MPS I) develop hyperintense white matter foci on T2-weighted brain magnetic resonance (MR) imaging that are associated clinically with cognitive impairment. We report here a diffusion tensor imaging (DTI) and tissue evaluation of white matter in a canine model...

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Publicado no:Exp Neurol
Main Authors: Provenzale, James M., Nestrasil, Igor, Chen, Steven, Kan, Shih-hsin, Le, Steven Q., Jens, Jacqueline K., Snella, Elizabeth M., Vondrak, Kristen N., Yee, Jennifer K., Vite, Charles H., Elashoff, David, Duan, Lewei, Wang, Raymond Y., Ellinwood, N. Matthew, Guzman, Miguel A., Shapiro, Elsa G., Dickson, Patricia I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644459/
https://ncbi.nlm.nih.gov/pubmed/26222335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.07.021
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