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Structure of the Spt16 Middle Domain Reveals Functional Features of the Histone Chaperone FACT
The histone chaperone FACT is an essential and abundant heterodimer found in all eukaryotes. Here we report a crystal structure of the middle domain of the large subunit of FACT (Spt16-M) to reveal a double pleckstrin homology architecture. This structure was found previously in the Pob3-M domain of...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624403/ https://ncbi.nlm.nih.gov/pubmed/23417676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.451369 |
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