An Attenuated Listeria monocytogenes Vector Primes More Potent Simian Immunodeficiency Virus-Specific Mucosal Immunity than DNA Vaccines in Mice

A human immunodeficiency virus type 1 (HIV-1) vaccine that induces potent immune responses in the gastrointestinal mucosa would be highly desirable. Here we show that attenuated recombinant Listeria monocytogenes, administered orally utilizing its natural route of infection, induces potent mucosal a...

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Detalhes bibliográficos
Main Authors: Im, Eung-Jun, Borducchi, Erica N., Provine, Nicholas M., McNally, Anna G., Li, Sufen, Frankel, Fred R., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624386/
https://ncbi.nlm.nih.gov/pubmed/23388715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03085-12
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