HIV-Specific CD8(+) T Cells from Elite Controllers Are Primed for Survival

HIV-specific cytotoxic T lymphocytes (CTL) are preferentially primed for apoptosis, and this may represent a viral escape mechanism. We hypothesized that HIV-infected individuals that control virus to undetectable levels without antiretroviral therapy (ART) (elite controllers [EC]) have the capacity...

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Bibliografiska uppgifter
Huvudupphovsmän: Yan, Jiyu, Sabbaj, Steffanie, Bansal, Anju, Amatya, Nilesh, Shacka, John J., Goepfert, Paul A., Heath, Sonya L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624329/
https://ncbi.nlm.nih.gov/pubmed/23449791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02379-12
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