Maribavir Inhibits Epstein-Barr Virus Transcription through the EBV Protein Kinase

Maribavir (MBV) inhibits Epstein-Barr virus (EBV) replication and the enzymatic activity of the viral protein kinase BGLF4. MBV also inhibits expression of multiple EBV transcripts during EBV lytic infection. Here we demonstrate, with the use of a BGLF4 knockout virus, that effects of MBV on transcr...

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Bibliografiske detaljer
Main Authors: Whitehurst, Christopher B., Sanders, Marcia K., Law, Mankit, Wang, Fu-Zhang, Xiong, Jie, Dittmer, Dirk P., Pagano, Joseph S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624302/
https://ncbi.nlm.nih.gov/pubmed/23449792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03505-12
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