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KIR2DL4 Copy Number Variation Is Associated with CD4(+) T-Cell Depletion and Function of Cytokine-Producing NK Cell Subsets in SIV-Infected Mamu-A*01-Negative Rhesus Macaques
Here, we demonstrate that KIR2DL4 copy number variation (CNV) is associated with CD4(+) T-cell decline and functionality of cytokine-producing NK cells during primary simian immunodeficiency virus (SIV) infection in Mamu-A*01(−) Indian-origin rhesus macaques, with higher KIR2DL4 copy numbers being a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624297/ https://ncbi.nlm.nih.gov/pubmed/23449795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02949-12 |
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