Association of Activating KIR Copy Number Variation of NK Cells with Containment of SIV Replication in Rhesus Monkeys

While the contribution of CD8(+) cytotoxic T lymphocytes to early containment of HIV-1 spread is well established, a role for NK cells in controlling HIV-1 replication during primary infection has been uncertain. The highly polymorphic family of KIR molecules expressed on NK cells can inhibit or act...

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Bibliographic Details
Main Authors: Hellmann, Ina, Lim, So-Yon, Gelman, Rebecca S., Letvin, Norman L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240609/
https://ncbi.nlm.nih.gov/pubmed/22194686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002436
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