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PEGylation of Vesicular Stomatitis Virus Extends Virus Persistence in Blood Circulation of Passively Immunized Mice

We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic virus is that human...

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Détails bibliographiques
Auteurs principaux: Tesfay, Mulu Z., Kirk, Amber C., Hadac, Elizabeth M., Griesmann, Guy E., Federspiel, Mark J., Barber, Glen N., Henry, Stephen M., Peng, Kah-Whye, Russell, Stephen J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624195/
https://ncbi.nlm.nih.gov/pubmed/23325695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02832-12
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