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Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements

Glucocorticoids are among the most potent and effective agents for treating inflammatory diseases and hematological cancers. However, subpopulations of patients are often resistant to steroid therapy, and determining the molecular mechanisms that contribute to glucocorticoid resistance is thus criti...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ramamoorthy, Sivapriya, Cidlowski, John A.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2013
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624172/
https://ncbi.nlm.nih.gov/pubmed/23428870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01151-12
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