Sphingosine 1-Phosphate induces filopodia formation through S1P2R activation of ERM proteins

Previously we demonstrated that the sphingolipids ceramide and sphingosine 1-phosphate (S1P) regulate phosphorylation of the ERM family of cytoskeletal proteins [1]. Herein, we show that exogenously applied or endogenously generated S1P (in a sphingosine kinase-dependent manner) result in significan...

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Main Authors: Gandy, K. Alexa Orr, Canals, Daniel, Adada, Mohamad, Wada, Masayuki, Roddy, Patrick, Snider, Ashley J., Hannun, Yusuf A., Obeid, Lina M.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623934/
https://ncbi.nlm.nih.gov/pubmed/23106337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120213
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