High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer

BACKGROUND: KRAS is an EGFR effector in the RAS/RAF/ERK cascade that is mutated in about 40% of metastatic colorectal cancer (mCRC). Activating mutations in codons 12 and 13 of the KRAS gene are the only established negative predictors of response to anti-EGFR therapy and patients whose tumors harbo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Guedes, Joana G, Veiga, Isabel, Rocha, Patrícia, Pinto, Pedro, Pinto, Carla, Pinheiro, Manuela, Peixoto, Ana, Fragoso, Maria, Raimundo, Ana, Ferreira, Paula, Machado, Manuela, Sousa, Nuno, Lopes, Paula, Araújo, António, Macedo, Joana, Alves, Fernando, Coutinho, Camila, Henrique, Rui, Santos, Lúcio L, Teixeira, Manuel R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623853/
https://ncbi.nlm.nih.gov/pubmed/23548132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-169
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados