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Importance of Relating Efficacy Measures to Unbound Drug Concentrations for Anti-Infective Agents
SUMMARY: For the optimization of dosing regimens of anti-infective agents, it is imperative to have a good understanding of pharmacokinetics (PK) and pharmacodynamics (PD). Whenever possible, drug efficacy needs to be related to unbound concentrations at the site of action. For anti-infective drugs,...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623378/ https://ncbi.nlm.nih.gov/pubmed/23554417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CMR.00092-12 |
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