Population Pharmacokinetic Modeling of the Unbound Levofloxacin Concentrations in Rat Plasma and Prostate Tissue Measured by Microdialysis

Levofloxacin is a broad-spectrum fluoroquinolone used in the treatment of both acute and chronic bacterial prostatitis. Currently, the treatment of bacterial prostatitis is still difficult, especially due to the poor distribution of many antimicrobials into the prostate, thus preventing the drug to...

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Главные авторы: Hurtado, Felipe K., Weber, Benjamin, Derendorf, Hartmut, Hochhaus, Guenther, Dalla Costa, Teresa
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
Предметы:
Experimental Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910848/
https://ncbi.nlm.nih.gov/pubmed/24217697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01884-13
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