Risk Factors for a Low Linezolid Trough Plasma Concentration in Acute Infections

Linezolid is an antibiotic with time-dependent activity, and both the percentage of time that plasma concentrations exceed the MIC and the area under the concentration-time curve over 24 h in the steady state divided by the MIC (AUC(24)/MIC ratio) are associated with clinical response. The aim of th...

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Detalhes bibliográficos
Main Authors: Morata, Laura, Cuesta, Marta, Rojas, Jhon F., Rodriguez, Sebastian, Brunet, Merce, Casals, Gregori, Cobos, Nazareth, Hernandez, Cristina, Martínez, José A., Mensa, Josep, Soriano, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623366/
https://ncbi.nlm.nih.gov/pubmed/23403416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01694-12
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