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Are Vancomycin Trough Concentrations Adequate for Optimal Dosing?

The current vancomycin therapeutic guidelines recommend the use of only trough concentrations to manage the dosing of adults with Staphylococcus aureus infections. Both vancomycin efficacy and toxicity are likely to be related to the area under the plasma concentration-time curve (AUC). We assembled...

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Hlavní autoři: Neely, Michael N., Youn, Gilmer, Jones, Brenda, Jelliffe, Roger W., Drusano, George L., Rodvold, Keith A., Lodise, Thomas P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910745/
https://ncbi.nlm.nih.gov/pubmed/24165176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01653-13
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