Are Vancomycin Trough Concentrations Adequate for Optimal Dosing?

The current vancomycin therapeutic guidelines recommend the use of only trough concentrations to manage the dosing of adults with Staphylococcus aureus infections. Both vancomycin efficacy and toxicity are likely to be related to the area under the plasma concentration-time curve (AUC). We assembled...

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Bibliografske podrobnosti
Main Authors: Neely, Michael N., Youn, Gilmer, Jones, Brenda, Jelliffe, Roger W., Drusano, George L., Rodvold, Keith A., Lodise, Thomas P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910745/
https://ncbi.nlm.nih.gov/pubmed/24165176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01653-13
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