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Identification of a cell-specific DNA-binding activity that interacts with a transcriptional activator of genes expressed in the acinar pancreas.

Footprint analysis of the 5'-flanking regions of the alpha-amylase 2, elastase 2, and trypsina genes, which are expressed in the acinar pancreas, showed multiple sites of protein-DNA interaction for each gene. Competition experiments demonstrated that a region from each 5'-flanking region interacted...

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Publicat a:Mol Cell Biol
Autors principals: Cockell, M, Stevenson, B J, Strubin, M, Hagenbüchle, O, Wellauer, P K
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362319/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2788241/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.6.2464-2476.1989
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