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Dynamic Regulation of the Translation Initiation Helicase Complex by Mitogenic Signal Transduction to Eukaryotic Translation Initiation Factor 4G

Eukaryotic translation initiation factor 4F (eIF4F), comprising the cap-binding protein eIF4E, the helicase eIF4A, and the central scaffold eIF4G, is a convergence node for a complex signaling network that controls protein synthesis. Together with eIF3 and eIF4A/4B, eIF4G recruits ribosomal subunits...

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Detalhes bibliográficos
Main Authors: Dobrikov, Mikhail I., Dobrikova, Elena Y., Gromeier, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623071/
https://ncbi.nlm.nih.gov/pubmed/23263986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01441-12
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