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Effects of etravirine on the pharmacokinetics and pharmacodynamics of warfarin in rats
BACKGROUND AND PURPOSE: Warfarin is often used with etravirine (ETV) to prevent HIV-related thromboembolic events. As both warfarin and ETV bind to plasma proteins and are metabolized by hepatic cytochrome P450s, they are likely to interact. Hence, we evaluated the effect of ETV on the pharmacokinet...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623055/ https://ncbi.nlm.nih.gov/pubmed/23215758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12082 |
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