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Cytopenia and Autoimmune Diseases: a Vicious Cycle fueled by mTOR Dysregulation in Hematopoietic Stem Cells

A long-standing but poorly understood defect in autoimmune diseases is dysfunction of the hematopoietic cells. Leukopenia is often associated with systemic lupus erythematous (SLE) and other autoimmune diseases. In addition, homeostatic proliferation of T cells, which is a host response to T cell ly...

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Detalles Bibliográficos
Main Authors: Zheng, Pan, Chang, Xing, Lu, Qianjin, Liu, Yang
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622805/
https://ncbi.nlm.nih.gov/pubmed/23375848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2012.12.011
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