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Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells
Genetic modification is critically enabling for studies addressing specification and maintenance of cell fate, however methods for engineering modifications are inefficient. We demonstrate a rapid and efficient recombination system in which an inducible, floxed cre allele replaces itself with an inc...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622722/ https://ncbi.nlm.nih.gov/pubmed/22039605 |
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