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Fragments of the Bacterial Toxin Microcin B17 as Gyrase Poisons
Fluoroquinolones are very important drugs in the clinical antibacterial arsenal; their success is principally due to their mode of action: the stabilisation of a gyrase-DNA intermediate (the cleavage complex), which triggers a chain of events leading to cell death. Microcin B17 (MccB17) is a modifie...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622597/ https://ncbi.nlm.nih.gov/pubmed/23593482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061459 |
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